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Acai Berry benefit by
Ray Sahelian, M.D.

Acai berry benefit
Apparently the dark purple skin of the acai berry has many times the anthocyanin content as red wine. The antioxidants in acai may benefit some health conditions but acai research in humans is quite limited. Acai berry also has plant sterols, essential fatty acids, and fiber. Human research is required before learning the potential acai berry benefit in medical conditions or prevention of health problems.
   Acai berry, in vitro, has a very high antioxidant capacity, especially for scavenging superoxide and peroxyl molecules. Compound in acai have also been found to have cyclooxygenase (COX)-1 and COX-2 inhibitor activity.

Acai Benefit as Vasodilator
Polyphenols in acai berry have the ability to act as vasodilators, which means they can dilate blood vessels. This means acai berry extract could benefit in conditions where blood vessel dilation is needed.

Endothelium-dependent vasodilator effect of Euterpe oleracea Mart. (Acai) extracts in mesenteric vascular bed of the rat.
Vascul Pharmacol. 2006 Sep 1; Department of Pharmacology and Psychobiology, IBRAG, UERJ, Rio de Janeiro, Brazil.
Acai (Euterpe oleracea Mart.) a fruit from the Amazon region, largely consumed in Brazil is rich in polyphenols. Experiments were undertaken to determine whether hydro-alcoholic extract obtained from acai induces a vasodilator effect in the rat mesenteric vascular bed precontracted with norepinephrine and, if so, to elucidate the underlying mechanism. The present study demonstrates that the vasodilator effect of acai extract is dependent on activation of nitric oxide -cGMP pathway and may also involve endothelium-derived hyperpolarizing factor release. The vasodilator effect suggest a possibility to use acai berry extract as a medicinal plant, in the treatment of cardiovascular diseases.

Acai berry availability
Acai is sold as capsules, and can be placed in smoothies or made into bars. You will also find acai berry made into acai juice. Acai pulp is also useful. Acai fruit juice and acai berry juice.

Acai Berry benefit Summary
Human studies with acai fruit or acai extract are lacking, therefore no firm statements can be made regarding the clinical uses of this plant. However, eating acai berry or taking an acai berry supplement as part of a healthy diet seems to be a reasonable approach. An acai berry extract supplement can be taken once or twice a week with breakfast.

Acai Berry nutrient composition
Phytochemical and Nutrient Composition of the Freeze-Dried Amazonian Palm Berry, Euterpe oleraceae Mart. ( Acai ).
J Agric Food Chem. 2006 Nov 1;54(22):8598-8603. Schauss AG, Wu X, Prior RL, Ou B, Patel D, Huang D, Kababick JP.
Natural and Medicinal Products Research, AIMBR Life Sciences, 4117 South Meridian, Puyallup, Washington 98373, Agriculture Research Service, Arkansas Children's Nutrition Center, U.S. Department of Agriculture, 1120 Marshall Street, Little Rock, Arkansas 72202, Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 4301 West Markham, Little Rock, Arkansas 72205, Brunswick Laboratories, 6 Thatcher Lane, Wareham, Massachusetts 02571, Integrated Biomolecule Corporation, 2005 E. Innovation Park Drive, Tucson, Arizona 85755, Food Science and Technology Program, Department of Chemistry, National University of Singapore, Singapore 117543, Singapore, and Flora Research, 32158 Camino Capistrano, San Juan Capistrano, California 92675.
A standardized freeze-dried acai fruit pulp / skin powder was used for all analyses and tests. Among many findings, anthocyanins, proanthocyanidins, and other flavonoids were found to be the major phytochemicals. Two anthocyanins, cyandin 3-glucoside and cyanidin 3-rutinoside were found to be predominant; three others were also found as minor anthocyanins. The total content of anthocyanins was measured as 3.1 mg/g dry weight. Polymers were found to be the major proanthocyanidins. The concentration of total proanthocyanidins was calculated as 13 mg/g dry weight Other flavonoids, namely, homoorientin, orientin, isovitexin, scoparin, and taxifolin deoxyhexose, along with several unknown flavonoids, were also detected. Resveratrol was found but at a very low concentration. In addition, components including fatty acids, amino acids, sterols, minerals, and other nutrients were analyzed and quantified. Total polyunsaturated fatty acid, total monounsaturated fatty acid, and total saturated fatty acids contributed to 11%, 60%, and 28% of total fatty acid. Oleic acid (53%) and palmitic acid (26%) were found to be the two dominant fatty acids. Nineteen amino acids were found; the total amino acid content was determined to be 7% of total weight. The total sterols accounted for 0.048% by weight of powder. The three sterols B-sitosterol, campesterol, and sigmasterol were identified.

Acai Tree
Euterpe oleraceae is a large palm tree indigenous to the Amazon River and its tributaries and estuaries in South America. Its fruit, known as acai, is of great economic value to native people.

Acai Berry Research - Latest Acai Research
Total oxidant scavenging capacities of Euterpe oleracea Mart. ( Acai ) fruits.
Int J Food Sci Nutr. 2005 Feb;56(1):53-64.
The antioxidant capacities of 11 commercial and non-commercial samples of Euterpe oleracea Mart. ( acai ) fruit pulp were studied with the total oxidant scavenging capacity assay in a modified and automated version against three reactive oxygen species. The antioxidant capacities of all purple acai samples were found to be excellent against peroxyl radicals, good against peroxynitrite and poor against hydroxyl radicals compared with common European fruit and vegetable juices recently analysed. In all cases the correlation between sample concentration and antioxidant capacities was non-linear. The antioxidant capacities against all three reactive oxygen species of the fruit pulp from one white acai variety were very low. The phenolic compounds in purple acai fruit pulp were identified by high-performance liquid chromatography-mass spectrometry, and the two major anthocyanins, cyanidin-3-glucoside and cyanidin-3-rutinoside, were quantified by high-performance liquid chromatography-visible spectrometry. The contributions of the anthocyanins to the overall antioxidant capacities of the fruit were estimated to be only approximately 10%. Obviously, compounds not yet identified are responsible for the major part of the antioxidant capacities of the acai fruit pulp.

Euterpe Oleracea ( Acai ) as an alternative oral contrast agent in MRI of the gastrointestinal system: preliminary results.
Magn Reson Imaging. 2004 Apr;22(3):389-93.
Using contrast agents is a common practice in medical imaging protocols. Paramagnetic properties of certain compounds present in contrast agents can affect magnetic resonance imaging (MRI) signals. For abdominal applications, they are usually injected, but may also be administered orally. However, their use as a routine technique is limited, mainly due to the lack of appropriate oral contrast agents. We herein present the preliminary characterization and results for implementation of Euterpe Oleracea (popularly named Acai) as a possible clinical oral contrast agent for MRI of the gastrointestinal tract. The pulp of Acai, a fruit from the Amazon area, presented an increase in T(1)-weighted MRI signal, equivalent to that of gadolinium-diethyltriamine pentaacetic acid, and a decrease in T(2)-weighted images. We looked for intrinsic properties that could be responsible for the T(1) signal enhancement and T(2) opacification. Atomic absorption spectra revealed the presence of Fe, Mn and Cu ions in Acai. The presence of such ions contribute to the susceptometric value found of chi = -4.83 x 10(-6). This finding assents with the hypothesis that image contrast changes were due to the presence of paramagnetic material. The first measurements in vivo demonstrate a clear increase of contrast, in T(1)-weighted images, due to the presence of Acai. Consistently, the opacification in a T(2)-weighted acquisition was evident, revealing a good contrast on bowel walls of gastric tissues.

Phytochemical composition and pigment stability of Acai (Euterpe oleracea Mart.).
J Agric Food Chem. 2004 Mar 24;52(6):1539-45. Del Pozo-Insfran D, Brenes CH, Talcott ST.
Department of Food Science and Human Nutrition, University of Florida, P.O. Box 110370, Gainesville, Florida
Anthocyanin and polyphenolic compounds present in acai (Euterpe oleracea Mart.) were determined and their respective contribution to the overall antioxidant capacity established. Color stability of acai anthocyanins against hydrogen peroxide (0 and 30 mmol/L) over a range of temperatures (10-30 degrees C) was also determined and compared to common anthocyanin sources. Additionally, stability in a model beverage system was evaluated in the presence of ascorbic acid and naturally occurring polyphenolic cofactors. Cyanidin 3-glucoside (1040 mg/L) was the predominant anthocyanin in acai and correlated to antioxidant content, while 16 other polyphenolics were detected from 4 to 212 mg/L. Red grape anthocyanins were most stable in the presence of hydrogen peroxide, while acai and pigments rich in acylated anthocyanins displayed lower color stability in a temperature-dependent manner. In the presence of ascorbic acid, acylated anthocyanin sources generally had increased color stability. Acai was recognized for its functional properties for use in food and nutraceutical products.

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